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Lori R · 06-29-2010, 09:10 PM

Courtney,
I think Chrisy makes a good point about questioning the Oncs further.

Seems like there could be some middle ground between 2 good options. Bear with me for a few random thoughts....could you take the Denosumab and see if it knocks down the markers? If you wait a month to see the results would the "big thaw" be done and you wouldn't have missed a beat on the U of W trail?

Many on the site have indicated Navelbine isn't as harsh yet appears to be very effective. So...not a bad choice either.

Sorry....not a lot of guidance here...can the U of W team provide a comittment that after Navelbine that you could jump back into the trial?

Certainly thinking of you. There is no "wrong" answer. Both approaches seem appropriate.

Please keep us posted....Lori

06-29-2010, 09:10 PM	#10
Lori R Senior Member Join Date: Jan 2008 Location: Evergreen, Colorado Posts: 454	Re: Treatment Decision Time Courtney, I think Chrisy makes a good point about questioning the Oncs further. Seems like there could be some middle ground between 2 good options. Bear with me for a few random thoughts....could you take the Denosumab and see if it knocks down the markers? If you wait a month to see the results would the "big thaw" be done and you wouldn't have missed a beat on the U of W trail? Many on the site have indicated Navelbine isn't as harsh yet appears to be very effective. So...not a bad choice either. Sorry....not a lot of guidance here...can the U of W team provide a comittment that after Navelbine that you could jump back into the trial? Certainly thinking of you. There is no "wrong" answer. Both approaches seem appropriate. Please keep us posted....Lori __________________ 2007 Oct - Diagnosed - Stage IV 5 c.m. IDC - Left Side er/pr- Her2+++ Node + 2/14 - Single Liver Met Double Mastectomy Nov - Begin T+H 2008 Feb-Complete 6 cycles- T&H- NED March - Continue - Herceptin Only April - Rads for 6 weeks 2009 Continue Herceptin - Continue NED April - Recurrance- 3 cm. Liver Met May - Cryosurgery June - November - Abraxane + Herceptin Aug - PET/CT - CTC = 0 Back to NED 2010 January - Continue NED July - Recurrance - 3 cm Liver Met CTC=1 August - Cryosurgery #2 August - November Navelbine November - Back to NED - End Navelbine 2011 Feb - Recur - 4 cm Liver Met - Same Left Lobe March Surgery it is -Couldn't get a clean margin July - Confirmed continued liver involvement August - Begin Herceptin + Tykerb October - Mixed results from H+T Add Abraxane + H + T - Nov - April 2012 January PET Scan - It's working!! April - Back to NED July - Recurrance August - Begin TDM-1 Trial (Taxol + TDM-1)