HER2 Support Group Forums - View Single Post - exciting preclinical finding re metformin (diabetes drug) killing cancer stem cell

jml · 05-12-2010, 12:08 PM

Hi All~
Just wanted to share that I've heard from a Research Coordinator @Simon Cancer Center at IUPUI that there ARE studies with Metformin & MBC coming down the pipeline...
Ironically, I was disqualified from their TDM1 trial because I have been on Metformin for a 7 years (for insulin resistance due to pre-med steroids, not for diabetes).
Even though the docs all agree with the preliminary research that supports Metformin, the unknown combo when combined with the study drug was deemed too uncertain & potentially toxic.
Still feeling very conflicted about all of this...

05-12-2010, 12:08 PM	#11
jml Senior Member Join Date: Dec 2006 Posts: 415	clinical trials coming soon... Hi All~ Just wanted to share that I've heard from a Research Coordinator @Simon Cancer Center at IUPUI that there ARE studies with Metformin & MBC coming down the pipeline... Ironically, I was disqualified from their TDM1 trial because I have been on Metformin for a 7 years (for insulin resistance due to pre-med steroids, not for diabetes). Even though the docs all agree with the preliminary research that supports Metformin, the unknown combo when combined with the study drug was deemed too uncertain & potentially toxic. Still feeling very conflicted about all of this...