HER2 Support Group Forums - View Single Post - ER+her2+ breast cancer may be fundamentally different in its response...

Ellie F · 05-07-2010, 04:24 AM

The debate rages on! I think Lani's comment about oversimplification of sub types of her 2 is certainly very relevant and as research continue I believe will bear this out.

Having recently had a bone marrow aspirate I am still CONFUSED about these sneaky cancer cell. Is the theory that csc just float around the blood stream forever, never dying just waiting for the opportunity to attach and grow? or are there csc produced in the bone marrow and then released into the bloodstream?If as a recent paper suggests they die after 3 days without signals does this mean there is a source in the bone marrow which harbours them and is never truly killed by any treatment? And what about women that never have a recurrence, does this mean that treatment has killed all the stem cells as well as circulating cancer cells?
Ellie

05-07-2010, 04:24 AM	#10
Ellie F Senior Member Join Date: Feb 2009 Posts: 1,526	Re: ER+her2+ breast cancer may be fundamentally different in its response... The debate rages on! I think Lani's comment about oversimplification of sub types of her 2 is certainly very relevant and as research continue I believe will bear this out. Having recently had a bone marrow aspirate I am still CONFUSED about these sneaky cancer cell. Is the theory that csc just float around the blood stream forever, never dying just waiting for the opportunity to attach and grow? or are there csc produced in the bone marrow and then released into the bloodstream?If as a recent paper suggests they die after 3 days without signals does this mean there is a source in the bone marrow which harbours them and is never truly killed by any treatment? And what about women that never have a recurrence, does this mean that treatment has killed all the stem cells as well as circulating cancer cells? Ellie