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Lani · 04-23-2010, 11:47 AM

Hopeful, in addition mmtvNEU tumors in mice are ER-.

Since her2 bc in humans comes in more than two flavors (ER+,ER-) it would seem obvious that other pathways are activated, they come from different Cancer stem cells/cancer progenitor cells, etc.

Inhibiting nfKappa beta and inflammation seems to be good idea in any case nevertheless, but I wouldn't overread too much into this, as almost all her2_ bc patients get chemo in addition to their herceptin and it is possible for this to change their blood-forming potential both long and shortterm.

04-23-2010, 11:47 AM	#4
Lani Senior Member Join Date: Mar 2006 Posts: 4,778	Re: Her2 anemia treatment may be different Hopeful, in addition mmtvNEU tumors in mice are ER-. Since her2 bc in humans comes in more than two flavors (ER+,ER-) it would seem obvious that other pathways are activated, they come from different Cancer stem cells/cancer progenitor cells, etc. Inhibiting nfKappa beta and inflammation seems to be good idea in any case nevertheless, but I wouldn't overread too much into this, as almost all her2_ bc patients get chemo in addition to their herceptin and it is possible for this to change their blood-forming potential both long and shortterm.