Thank you, Lani!
I have been following the Herceptin/PI3 kinase inhibitor combination for a while. Check out this poster from a company named ARRAY which makes a PI3 kinase inhibitor called ARRY 380. It shows that, in lab mice, this combo had a 100% cure rate!
http://www.arraybiopharma.com/_docum...achment337.pdf
ARRY 380 is currently in clinical trial as a single agent at M.D. Anderson.
However, for those of you interested in a clinical trial combining BOTH a version of Herceptin (T-DM1) and a PI3 kinase inhibitor, Dana Farber currently has one in a Phase I trial. I met with Dr. Ian Krop in December to discuss joining but he suggested I wait until it reaches Phase II as it is coming to UCSF - where I live. Here is a link to the Dana Farber trial:
http://clinicaltrials.gov/ct2/show/N...cr=Open&rank=6