HER2 Support Group Forums - View Single Post - Reposting for "cynthia1962"...needs help please.

Chelee · 11-01-2009, 03:34 PM

Hi Cynthia, I know your new here & learning how the board works. You almost have it wired.

I found your question buried in another thread & decided start a new thread for you so more people would see it and be able to help you. (Hope you don't mind?) Any time you have a new question it's always good to start an entirely "new" thread. You do that by looking up at the top of the board on the left hand side and click on the button that says, "New Thread". Compose your question & hit the "send" button.

For all are Her2 members...here is Cynthia's question she needs help with. Thanks to all of you.
Chelee
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Hello everybody;

Newby in the house again.
You made me look at my pathology report for numbers. I don't know what none of it means but here it is Her2neu specific immostain tissue; 10% buffered. No staining or membrane staining in 10% of tumor cells 1+negative. Faint membrane staining in 10% of toumor cells only part of the membrane is 2+ week postive. Week/moderate complete membrane staining in 10% cells 3+ strong positive. Strong complete membrane staining in 10% tumor cells. So I have three numbers what do they mean anybody no.
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Age 47, TN
Infiltrating Ductal Carcinoma of Breast, Grade 2 Stage IIA, Estrogen Receptor Positive, Gross Description 0.5cm up to 1.2cm in length with an average diameter of 0.1cm

11-01-2009, 03:34 PM	#1
Chelee Senior Member Join Date: Feb 2006 Location: Southern, CA Posts: 2,511	Reposting for "cynthia1962"...needs help please. Hi Cynthia, I know your new here & learning how the board works. You almost have it wired. I found your question buried in another thread & decided start a new thread for you so more people would see it and be able to help you. (Hope you don't mind?) Any time you have a new question it's always good to start an entirely "new" thread. You do that by looking up at the top of the board on the left hand side and click on the button that says, "New Thread". Compose your question & hit the "send" button. For all are Her2 members...here is Cynthia's question she needs help with. Thanks to all of you. Chelee ----------------------------------------------------------------------------- Hello everybody; Newby in the house again. You made me look at my pathology report for numbers. I don't know what none of it means but here it is Her2neu specific immostain tissue; 10% buffered. No staining or membrane staining in 10% of tumor cells 1+negative. Faint membrane staining in 10% of toumor cells only part of the membrane is 2+ week postive. Week/moderate complete membrane staining in 10% cells 3+ strong positive. Strong complete membrane staining in 10% tumor cells. So I have three numbers what do they mean anybody no. __________________ Age 47, TN Infiltrating Ductal Carcinoma of Breast, Grade 2 Stage IIA, Estrogen Receptor Positive, Gross Description 0.5cm up to 1.2cm in length with an average diameter of 0.1cm __________________ DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes. Rt. MRM on 1-3-06 -- No Rads due to compromised lungs. Chemo started 2-7-06 -- TCH - - Finished 6-12-06 Finished yr of wkly herceptin 3-19-07 3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07 9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV. 9-28-09 Loading dose of Herceptin & started Zometa 9-29-09 Power Port Placement 10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head. 11-19-09 RT. Femur surgery - Rod placed 12-7-09 Navelbine added to Herceptin/Zometa. 3-23-10 Ten days of rads to RT femur. Completed. 4-05-10 Quit Navelbine--Herceptin/Zometa alone. 5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy. Results to FISH was unsuccessful--this happens less then 2% of the time. 7-7-10 Recurrence to RT axilla again. Back to UCLA for options.