HER2 Support Group Forums - View Single Post - Researchers Ponder Shorter Course of AI therapy

DianneS · 08-28-2009, 09:18 PM

Interesting. I feel like a yo-yo. One day I think I should try AI's. The next I'm thinking I've had enough!

My onc is suggesting maybe we'll try couple years of Tamoxifen then follow it with an AI. I could not tolerate Arimidex; it caused nausea daily.

What other side effects do AI's possibly cause? Sarah, you mentioned 'weird hands and feet' ?? What else can one expect from these wonder drugs?

Diannes

08-28-2009, 09:18 PM	#12
DianneS Senior Member Join Date: Aug 2008 Posts: 327	Re: Researchers Ponder Shorter Course of AI therapy Interesting. I feel like a yo-yo. One day I think I should try AI's. The next I'm thinking I've had enough! My onc is suggesting maybe we'll try couple years of Tamoxifen then follow it with an AI. I could not tolerate Arimidex; it caused nausea daily. What other side effects do AI's possibly cause? Sarah, you mentioned 'weird hands and feet' ?? What else can one expect from these wonder drugs? Diannes __________________ Three years and 5 months NED Dx: Aug 2008 right breast IDC with 50% of tumor DCIS, Stage II or IIA, tumor size: 2.1 cm Grade 3 8/9 Richardson/Bloom test ER+ weakly positive Alred Score: 4 (suggesting I would strongly benefit from hormone therapy) PR-, HER2 positive +++ No vascular invasion No lymph nodes involved Surgery: Sept. 9, 2008 -Modified radical mastectomy, right breast. I chose to have a simple mastectomy on the left. Began Taxotere/Carboplatin/Herceptin November, 2008. Finished T/C March 2009. Finished #16 Herceptin Sept. 09. AI's and Tamoxifen made me sick. Began natural Tamoxifen which is Quercetin, I3C and a combo of other supplements. I am also a DES Daughter. There is now a link between DES exposure in utero and breast cancer!