HER2 Support Group Forums - View Single Post - Vaccine Therapy in Treating Patients With Breast Cancer

Ellie F · 07-30-2009, 11:08 AM

Hi Steph
CEA is the protein measured for your tumour markers.This trial is NCT00673829 at Roger Williams Medical Centre, Rhode Island. It is funded by an IMPACT grant.The estimate is that between 30-50% of metastatic breast cancer tumours express this protein.My understanding is that if your serum cea>=10ng/ml you automatically qualify for the trial. If your serum cea<10ng/ml tumour tissue must be tested to see if you will qualify.
The second trial is the phase1/2 Quantum imm trial highlighted on clinical trials on the board.This is targeted against oncofetal antigens which apparently have a high percentage on bc tumours.
My onc feels that these are very early developments which will look at safety levels and tolerability. But they have at least 5 years to run so progress will no doubt gallop on.
Hope this is some help
Ellie

07-30-2009, 11:08 AM	#10
Ellie F Senior Member Join Date: Feb 2009 Posts: 1,526	Re: Vaccine Therapy in Treating Patients With Breast Cancer Hi Steph CEA is the protein measured for your tumour markers.This trial is NCT00673829 at Roger Williams Medical Centre, Rhode Island. It is funded by an IMPACT grant.The estimate is that between 30-50% of metastatic breast cancer tumours express this protein.My understanding is that if your serum cea>=10ng/ml you automatically qualify for the trial. If your serum cea<10ng/ml tumour tissue must be tested to see if you will qualify. The second trial is the phase1/2 Quantum imm trial highlighted on clinical trials on the board.This is targeted against oncofetal antigens which apparently have a high percentage on bc tumours. My onc feels that these are very early developments which will look at safety levels and tolerability. But they have at least 5 years to run so progress will no doubt gallop on. Hope this is some help Ellie