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In addition to whatever tissue biospy is evaluable, you might want the serum her2 test to add to the picture. Elevation suggests benefit from Herceptin. ANd benefit is being considered even after progression. And it could argue in favor of getting Lapatinib(Tykerb). Also..keep in mind there is some suggestion that cancer stem cells(CSC) are ER-, Her 2 positive..despite what the majority of tumor cells show. in other words, all BC might be her2+ in a very important way. Current indications are that Lapatinib is one of a few available therapies that address CSC.
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