HER2 Support Group Forums - View Single Post - MUST DECIDE ASAP-NEED INFO on IXEMPRA and DOXIL Doxil

Believe51 · 07-03-2009, 02:29 PM

Lida, Ed has taken his 3rd infusion of Ixempra on the 26th. This time he is a little more sick with body aches/bone pain. And Kavy, I told him to rest, rest, rest and that is exactly what he is doing. I cannot remember offhand what his dose is but I am thinking of lowering it. His tumor markers went down 120 points in two and a half weeks.

We will not add Herceptin since it stopped working for him in the past. It is still an option with some other combos for him though. I would like to see if this drug passes the BBB and enters his brain. I do not know of anyone using this alone and with active brain mets. Wow, would I love to broadcast that one! Ixempra has a sister drug that does pass the BBB. In the meantime gang, this is working for many and I wish this to be our magic potion.

If we do stop the Ixempra for any reason, it will be to start another regime. Right now I would like to start him on Temodar for the brain mets but am curious as to what the Ixempra may be helping his brain with.

Good luck to us all as we embark on this drug together.>>Believe51

07-03-2009, 02:29 PM	#13
Believe51 Senior Member Join Date: Jun 2007 Location: RHODE ISLAND (Ed getting me a latte on 2nd Cancerversary Cruise 2008) 'BELIEVE': To accept as true or real, To have faith in, To presume ALWAYS BELIEVE Posts: 2,999	Lida, Ed has taken his 3rd infusion of Ixempra on the 26th. This time he is a little more sick with body aches/bone pain. And Kavy, I told him to rest, rest, rest and that is exactly what he is doing. I cannot remember offhand what his dose is but I am thinking of lowering it. His tumor markers went down 120 points in two and a half weeks. We will not add Herceptin since it stopped working for him in the past. It is still an option with some other combos for him though. I would like to see if this drug passes the BBB and enters his brain. I do not know of anyone using this alone and with active brain mets. Wow, would I love to broadcast that one! Ixempra has a sister drug that does pass the BBB. In the meantime gang, this is working for many and I wish this to be our magic potion. If we do stop the Ixempra for any reason, it will be to start another regime. Right now I would like to start him on Temodar for the brain mets but am curious as to what the Ixempra may be helping his brain with. Good luck to us all as we embark on this drug together.>>Believe51 __________________ 9/7/06Husband 50yrs=StageIV IBC/HER2+,BoneMets10/06TaxotereX10,'H'1X wk,Zometa,Tamoxifen4/12/07Last Tax5/18/07Pet=Rapid Cell Activity,No Organ Mets,Lytic Lesions,Degeneration,Some Bone Repair5/07ChemoFail6/01/07Pleural Thoracentisis=Effusions,NoMalignantCells6/19/07+7/2/07DFCI 6/25/07BrainMRI=BrainMets,Many<9mm7/10/07WBR/PelvisRad37.5Gx15&Nutritionist8/19/07T/X9/20/07BrainMRI=2<2mm10/6/07Pet=BoneProgression 10/24/07ChemoFail11/9/07A/Cx10,EndTam12/7/07Faslodex12/10/07Muga7512/13/07BlasticLesions1/7/08BrainMRI=Clear4/1/08Pet=BoneImprovement, NoProgression,Stable4/7/08BrainPerfect5/16/08Last A/C8/26/08BrainMets=10(<9mm)9/10/08Gamma10/30/08Met=5mm12/19/08Gamma5mets5 12/22/08SpinalMets1/14/09SpinalRads2/17/09BrainMRI=NoNewMets4/20/09BoneScan5/14/09Ixempra6/1/09BrainMRI=NumerousMets6/24/09DFCIw/DrBurstein6/26/09Continue Ixempra/Faslodex/Zometa~TM now lower7/17/09Stop Ixempra By Choice9/21/09HOSPICE10/16/09Earned His Deserved Wings And Halo=37 Month Fight w/Stage 4 IBC, Her2+++,My Hero!!