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Debbie L. · 06-14-2009, 06:57 PM

Hi,

I've heard of many issues with AI's but not increased head/neck and lung cancers. Can you send us a link to what you read?

How positive was your ER? Did they provide a number value? Where was this ER done? If not at a Comprehensive Cancer Center:

http://cancercenters.cancer.gov/canc...ers/index.html ,

I'd suggest that you send (or have your lab send) your tissue blocks and slides for a second-opinion on ERPR.

My cancer was said to be weakly ER+ also, at my local facility. Two years later (after 2 years of useless arimidex), I sent the tissue blocks to Baylor and it was found to be totally ERPR negative.

Before delving into your other excellent questions (how effective is an AI for low ER levels?), I'd want to confirm the test itself.

Debbie Laxague

06-14-2009, 06:57 PM	#8
Debbie L. Senior Member Join Date: Jul 2006 Posts: 463	new side effect? Hi, I've heard of many issues with AI's but not increased head/neck and lung cancers. Can you send us a link to what you read? How positive was your ER? Did they provide a number value? Where was this ER done? If not at a Comprehensive Cancer Center: http://cancercenters.cancer.gov/canc...ers/index.html , I'd suggest that you send (or have your lab send) your tissue blocks and slides for a second-opinion on ERPR. My cancer was said to be weakly ER+ also, at my local facility. Two years later (after 2 years of useless arimidex), I sent the tissue blocks to Baylor and it was found to be totally ERPR negative. Before delving into your other excellent questions (how effective is an AI for low ER levels?), I'd want to confirm the test itself. Debbie Laxague __________________ 3/01 ~ Age 49. Occult primary announced by large (6cm) axillary node, found by my husband. 4/01 ~ Bilateral mastectomies (LMRM, R elective simple) - 1.2cm IDC was found at pathology. 5 of 11 axillary nodes positive, largest = 6cm. Stage IIIA ERPR 5%/1% (re-done later at Baylor, both negative at zero). HER2neu positive by IHC and FISH (8.89). Lymphovascular invasion, grade 3, 8/9 modified SBR. TX: Control of arm of NSABP's B-31 adjuvant Herceptin trial (no Herceptin, inducing a severe case of Herceptin-envy): A/C x 4 and Taxol x 4 q3weeks, then rads. Raging infection of entire chest after small revision of mastectomy scar after completing tx (significance unknown). Arimidex for two years, stopped after second pathology opinion. 2017: Mild and manageable lymphedema and some cognitive issues.