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You might want to list all prior treatments she's had to help people get ideas. If you look in articles of interest, I did post there about fulvestrant + chemo synergy. Perhaps it would make sense to add that to what she was just on. Might depend on the severity of the progression. i.e. would it benefit by a little something extra or is it totally failing. I think it might be wise to ask the onc about their view on cancer stem cells. Herceptin and Tykerb are both purported to kill CSC so the doc may be onto something.
Regarding TDM1 trial, I believe there were folks saying that certain characteristics were predictive of response. Might look into that issue while in holding pattern.
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