I don't know about Ixempra vs Doxil but...seems to be a lot of support recently for continuing Herceptin after progression on it. I believe Doxil is supposed to be better cardio wise than Adriamycin.
http://professional.cancerconsultant....aspx?id=36971
And the FDA has approved a cardio preventative:
http://www.cancer.gov/cancertopics/d...-hydrochloride
discussion on DOXIL + H here:
http://community.breastcancer.org/forum/8/topic/725181
Have you had Tykerb? Are you ER+?
What is your chemo background? What is the bili at?