HER2 Support Group Forums - View Single Post - Roche to present major advances with targeted cancer medicines at ASCO

Barbara2 · 05-16-2009, 07:06 PM

Basel, 14 May 2009. /PRNewswire/ — Roche today provided an overview of results from studies that further the company's approach to developing targeted medicines for people with cancer, a diagnosis that will affect more than one in three people during their lifetime. Results from studies involving the company's approved and investigational treatments will be presented during the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO) taking place May 29 through June 2 in Orlando, USA.

New combination approach to attack HER2-positive breast cancer

Final efficacy results will be presented from a Phase II study (TDM4258g) of T-DM1 in women whose breast cancer had progressed following previous treatment with two or more HER2-targeted therapies. These patients who have nearly no treatment options left, still could benefit from T-DM1. T-DM1 is a novel antibody-drug combination that links Herceptin and the cell-killing agent DM1. A Phase III study (EMILIA) evaluating T-DM1 for second-line advanced HER2-positive breast cancer was initiated this year.

05-16-2009, 07:06 PM	#1
Barbara2 Senior Member Join Date: Sep 2005 Location: South Dakota. Posts: 621	Roche to present major advances with targeted cancer medicines at ASCO Basel, 14 May 2009. /PRNewswire/ — Roche today provided an overview of results from studies that further the company's approach to developing targeted medicines for people with cancer, a diagnosis that will affect more than one in three people during their lifetime. Results from studies involving the company's approved and investigational treatments will be presented during the 45th Annual Meeting of the American Society of Clinical Oncology (ASCO) taking place May 29 through June 2 in Orlando, USA. New combination approach to attack HER2-positive breast cancer Final efficacy results will be presented from a Phase II study (TDM4258g) of T-DM1 in women whose breast cancer had progressed following previous treatment with two or more HER2-targeted therapies. These patients who have nearly no treatment options left, still could benefit from T-DM1. T-DM1 is a novel antibody-drug combination that links Herceptin and the cell-killing agent DM1. A Phase III study (EMILIA) evaluating T-DM1 for second-line advanced HER2-positive breast cancer was initiated this year. __________________ Blessings and Peace, Barbara DX Oct 02 @ age 52 Stage 2B Grade 3 Mastectomy "at least" 4.5 cm IDC 1+node ER+61% /PR- Assiciated Intraductual component with Comedo Necrosis Her2+ FISH8.6 IHC 2+ 5 1/2 CEF Arimidex Celebrex 400mg daily for 13 months Prophylactic mastectomy Estradiol #: 13 PTEN positive, "late" Herceptin (26 months after chemo) Oct 05: Actonel for osteopenia from Arimidex. May 08: Replaced Actonel with Zometa . Taking every 6 months. Accepting the gift of life, I give thanks for it and live it in fullness.