HER2 Support Group Forums - View Single Post - DM-1 thoughts

Rich66 · 04-30-2009, 04:54 PM

I wonder if financial agreements/funding are the only reason Immunogen is combining DM1 solely with Traz(Herceptin). If the other T, Tykerb, has a second receptor (her1) to bring the DM1 to..why not? Sounds like double the displeasure for the cancer cell.
I also wonder whether hormone (or other) receptor treatments could deliver the DM1. Is DM1's mechanism only effective on Her2+ cells?

04-30-2009, 04:54 PM	#1
Rich66 Senior Member Join Date: Feb 2008 Location: South East Wisconsin Posts: 3,431	DM-1 thoughts I wonder if financial agreements/funding are the only reason Immunogen is combining DM1 solely with Traz(Herceptin). If the other T, Tykerb, has a second receptor (her1) to bring the DM1 to..why not? Sounds like double the displeasure for the cancer cell. I also wonder whether hormone (or other) receptor treatments could deliver the DM1. Is DM1's mechanism only effective on Her2+ cells?