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Jean · 03-06-2009, 02:51 PM

I am moving this post over to this area as you may recive additonal information.

robind
Member

Join Date: Aug 2008
Location: Central,New Jersey
Posts: 17

ER/PR weak, Her2 Positive vs. Femera
3 months into receiving Herceptin, just started Femera. Oncologist said Femera won't be as effective in my case because I am weakly er/pr positive (both 15%). If I were strongly er/pr positive I would benefit much more. She gave me the impression that my prognosis is not as good because of this or maybe I was so shocked to learn the above that's what I read into it. My question now has become then why would I take Femera to begin with? If I am considered weakly, and the benefits are not so high than what real benefit will it be? The side effects might not be worth it if I am not going to benefit from taking this drug for 5 years. My bc tumor was 1.4cm, stage1 upgraded to stage 2 with cells in 1 sentinel node. Her2 positive (3.1 amplified), clear margins, IDC.
Is anyone out here weakly er/pr positive but her2 positive that is receiving Herceptin but not taking a Aromotose Inhibitor?

03-06-2009, 02:51 PM	#1
Jean Senior Member Join Date: Oct 2005 Location: New Jersey Posts: 3,154	er/pr weak... I am moving this post over to this area as you may recive additonal information. robind Member Join Date: Aug 2008 Location: Central,New Jersey Posts: 17 ER/PR weak, Her2 Positive vs. Femera 3 months into receiving Herceptin, just started Femera. Oncologist said Femera won't be as effective in my case because I am weakly er/pr positive (both 15%). If I were strongly er/pr positive I would benefit much more. She gave me the impression that my prognosis is not as good because of this or maybe I was so shocked to learn the above that's what I read into it. My question now has become then why would I take Femera to begin with? If I am considered weakly, and the benefits are not so high than what real benefit will it be? The side effects might not be worth it if I am not going to benefit from taking this drug for 5 years. My bc tumor was 1.4cm, stage1 upgraded to stage 2 with cells in 1 sentinel node. Her2 positive (3.1 amplified), clear margins, IDC. Is anyone out here weakly er/pr positive but her2 positive that is receiving Herceptin but not taking a Aromotose Inhibitor? __________________ Stage 1, Grade 1, 3/30/05 Lumpectomy 4/15/05 - 6MM IDC Node Neg. (Sentinel node) ER+ 90% / PR-, Her2+++ by FISH Ki-67 40% Arimidex 5/05 Radiation 32 trt, 5/30/05 Oncotype DX test 4/17/06, 31% high risk TOPO 11 neg. 4/06 Stopped Arimidex 5/06 TCH 5/06, 6 treatments Herceptin 5/06 - for 1 yr. 9/06 Completed chemo Started Femara Sept. 2006