HER2 Support Group Forums - View Single Post

Laurel · 02-02-2009, 06:27 PM

Maria,

Looking at your signature it indicates you are only 10% E.R. +. Is this correct? If so, I am not surprised you are not experiencing symptoms and are menstruating again. Frankly, I did not think there was any benefit with estrogen suppressors for E.R. positive below 70%, but I may be recalling that wrongly. I have heard of several younger women menstruating while taking Tamoxifen. I am participating in a Tamoxifen study where they do testing to see if I am synthesizing the drug properly and able to benefit from it. These labs will be drawn at my next exam in mid-March. I will try to remember to email you the names of the tests.

It seems you are correct to be questioning the efficacy of that drug, especially given its side effects vs benefit.

02-02-2009, 06:27 PM	#2
Laurel Senior Member Join Date: May 2008 Location: Hershey, PA. Live The Sweet Life! Posts: 2,005	Maria, Looking at your signature it indicates you are only 10% E.R. +. Is this correct? If so, I am not surprised you are not experiencing symptoms and are menstruating again. Frankly, I did not think there was any benefit with estrogen suppressors for E.R. positive below 70%, but I may be recalling that wrongly. I have heard of several younger women menstruating while taking Tamoxifen. I am participating in a Tamoxifen study where they do testing to see if I am synthesizing the drug properly and able to benefit from it. These labs will be drawn at my next exam in mid-March. I will try to remember to email you the names of the tests. It seems you are correct to be questioning the efficacy of that drug, especially given its side effects vs benefit. __________________ Smile On! Laurel Dx'd w/multifocal DCIS/IDS 3/08 7mm invasive component Partial mast. 5/08 Stage 1b, ER 80%, PR 90%, HER-2 6.9 on FISH 0/5 nodes 4 AC, 4 TH finished 9/08 Herceptin every 3 weeks. Finished 7/09 Tamoxifen 10/08. Switched to Femara 8/09 Bilat SPM w/reconstruction 10/08 Clinical Trial w/Clondronate 12/08 Stopped Clondronate--too hard on my gizzard! Switched back to Tamoxifen due to tendon pain from Femara 15 Years NED I think I just might hang around awhile....