HER2 Support Group Forums - View Single Post - for those with ER+her2+ breast cancer, an important article

Jean · 01-20-2009, 09:02 PM

Hi Lani,
Thank you, as always for posting the latest news that is so vital.

I especially enjoyed reading this new article since it supports what Dr. Slamon has been saying the past few years. I have been a bit concerned with the treatment of herceptin alone (maybe the future will be that) but for now the studies have been showing that herceptin works best along with chemo.

Several large studies demonstrated that trastuzumab significantly improves disease-free and overall survival when given in combination with, or following, chemotherapy, regardless of hormone receptor status.

This new article should hold very special value to those who are not sure about the chemo/hercpetin combo.
For now it is showing and demonstrating that is what we "have" that is showing results, until we can have studies showing other wise. I believe as we advance in research and drugs the day will finaly arrive when the chemo maybe dropped.

Great information in regards to AI proving to work in harmony with herceptin. If we all search back Becky has mentioned this about 2.5 yrs ago from early studies.

As I have said often to newly dx early stage sisters, the stats are not in yet - we may also soon see from studies that herceptin given to all her2....will change the face of this disease....

Each day we get a bit closer.
Thanks Lanie,

01-20-2009, 09:02 PM	#7
Jean Senior Member Join Date: Oct 2005 Location: New Jersey Posts: 3,154	Hi Lani, Thank you, as always for posting the latest news that is so vital. I especially enjoyed reading this new article since it supports what Dr. Slamon has been saying the past few years. I have been a bit concerned with the treatment of herceptin alone (maybe the future will be that) but for now the studies have been showing that herceptin works best along with chemo. Several large studies demonstrated that trastuzumab significantly improves disease-free and overall survival when given in combination with, or following, chemotherapy, regardless of hormone receptor status. This new article should hold very special value to those who are not sure about the chemo/hercpetin combo. For now it is showing and demonstrating that is what we "have" that is showing results, until we can have studies showing other wise. I believe as we advance in research and drugs the day will finaly arrive when the chemo maybe dropped. Great information in regards to AI proving to work in harmony with herceptin. If we all search back Becky has mentioned this about 2.5 yrs ago from early studies. As I have said often to newly dx early stage sisters, the stats are not in yet - we may also soon see from studies that herceptin given to all her2....will change the face of this disease.... Each day we get a bit closer. Thanks Lanie, __________________ Stage 1, Grade 1, 3/30/05 Lumpectomy 4/15/05 - 6MM IDC Node Neg. (Sentinel node) ER+ 90% / PR-, Her2+++ by FISH Ki-67 40% Arimidex 5/05 Radiation 32 trt, 5/30/05 Oncotype DX test 4/17/06, 31% high risk TOPO 11 neg. 4/06 Stopped Arimidex 5/06 TCH 5/06, 6 treatments Herceptin 5/06 - for 1 yr. 9/06 Completed chemo Started Femara Sept. 2006