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dlaxague · 11-17-2008, 10:06 AM

serum her2 ECD if performed BEFORE&after surgery may help predict herceptin efficacy

Thanks for taking the time to post all those, Lani. But I don't understand how you drew the above conclusion. It sounds to me like serum HER2 ECD is basically just another tumor marker. Useful for following treatment of mets, and maybe giving information about treatment efficacy sooner than scans, but of little if any use adjuvantly. And I don't see anything at all about its ability to predict Herceptin efficacy in adjuvant disease. Did I skim too fast? Do you have time to explain?

Thanks for keeping us educated,
Debbie Laxague

11-17-2008, 10:06 AM	#9
dlaxague Senior Member Join Date: May 2006 Posts: 221	I don't follow ... serum her2 ECD if performed BEFORE&after surgery may help predict herceptin efficacy Thanks for taking the time to post all those, Lani. But I don't understand how you drew the above conclusion. It sounds to me like serum HER2 ECD is basically just another tumor marker. Useful for following treatment of mets, and maybe giving information about treatment efficacy sooner than scans, but of little if any use adjuvantly. And I don't see anything at all about its ability to predict Herceptin efficacy in adjuvant disease. Did I skim too fast? Do you have time to explain? Thanks for keeping us educated, Debbie Laxague