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The Efects trial used hormone positive metastatic women who failed on Arimidex. Half were give Faslodex shots and the other half were given Aromosin. Astro Zeneca was probably hopeful that Faslodex would "win" since it not only makes Faslodex but the "failed" Arimidex (thereby keeping the business). The trial showed Faslodex and Aromosin to be equal in effect. What the trial showed was metastatic women who fail Arimidex can switch to another pill form of anti-hormonal (as Faslodex is a shot).
Aromosin works in a different way (biochemically) to suppress the action of aromatase than Arimidex and Femara work (they are different drugs but work the same way). I don't know if one or another causes more weight gain or not.
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Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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