HI,
I did some searching and found this abstract - might be worth trying.
The abstract is short, so I am posting it.
Symptomatic and neurophysiological responses of paclitaxel- or cisplatin-induced neuropathy to oral acetyl-L-carnitine
Acetyl-L-carnitine (ALC) improves non-oncological neuropathies. We rested oral ALC (1 g tid) for 8 weeks in 25 patients with neuropathy grade ≥3 (common toxicity criteria CTC) during paclitaxel or eisplalin therapy, or grade ≥2 persisting for at least three months after discontinuing the drugs. An independent neurologist assessed patients before and after ALC. All patients except one reported symptomatic relief, and only two described grade I nausea. The sensory neuropathy grade improved in IS of 25 (60%), and motor neuropathy in 11 of 14 patients (79%). Total neuropathy score (TNS) that included neurophysiological measures improved in 23 (92%). Amelioration of sensory amplitude and conduction velocity (sural and peroneal nerves) was measured in 22 and 21 patients, respectively. Symptomatic improvement persisted in 12 of 13 cvaluahle patients at median 13 months after ALC. In view of its effect in improving established paclitaxel- and cisplatin-neuropathy, we recommend ALC testing in preventing progression or revert symptoms dining neurotoxic chemotherapy.
http://cat.inist.fr/?aModele=afficheN&cpsidt=17074156