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Joan M · 07-18-2008, 02:27 PM

Sherry, Hopefully it's just a cyst. It's hard to predict the future, so don't kick yourself in the butt. I understand though how you feel but from a different perspective. In 2000 I had a full hysterectomy and then took Premarin for three years. Two days after going off the drug a mammogram showed two nodules in my right breast -- one DCIS and one infiltrating bc -- and I often think that the immediate menopause in combination with the Premarin initiated my bc growth, that it threw my immune system into a tailspin. Even though there was nothing wrong with my ovaries, I had them removed along with my uterus which had very large fibroids, because every medical professional was warning me about ovarian cancer, saying that if I removed the ovaries, I wouldn't have to worry about it every again. Yeah, well I guess that's true. But we never know what else can happen. I'm praying that everything will be okay. Best, Joan

07-18-2008, 02:27 PM	#3
Joan M Senior Member Join Date: Oct 2007 Posts: 1,851	Sherry, Hopefully it's just a cyst. It's hard to predict the future, so don't kick yourself in the butt. I understand though how you feel but from a different perspective. In 2000 I had a full hysterectomy and then took Premarin for three years. Two days after going off the drug a mammogram showed two nodules in my right breast -- one DCIS and one infiltrating bc -- and I often think that the immediate menopause in combination with the Premarin initiated my bc growth, that it threw my immune system into a tailspin. Even though there was nothing wrong with my ovaries, I had them removed along with my uterus which had very large fibroids, because every medical professional was warning me about ovarian cancer, saying that if I removed the ovaries, I wouldn't have to worry about it every again. Yeah, well I guess that's true. But we never know what else can happen. I'm praying that everything will be okay. Best, Joan __________________ Diagnosed stage 2b in July 2003 (2.3 cm, HER2+, ER-/PR-, 7+ nodes). Treated with mastectomy (with immediate DIEP flap reconstruction), AC + T/Herceptin (off label). Cancer advanced to lung in Jan. 2007 (1 cm nodule). Started Herceptin every 3 weeks. Lung wedge resection April 2007. Cancer recurred in lung April 2008. RFA of lung in August 2008. 2nd annual brain MRI in Oct. 2008 discovered 2.6 cm cystic tumor in left frontal lobe. Craniotomy Oct. 2008 (ER-/PR-/HER2-) followed by targeted radiation (IMRT). Coughing up blood Feb. 2009. Thoractomy July 2009 to cut out fungal ball of common soil fungus (aspergillus) that grew in the RFA cavity (most likely inhaled while gardening). No cancer, only fungus. Removal of tiny melanoma from upper left arm, plus sentinel lymph node biopsy in Feb. 2016. Guardant Health liquid biopsy in Feb. 2016 showed mutations in 4 subtypes of TP53. Repeat of Guardant Health biopsy in Jana. 2021 showed 3 TP53 mutations, BRCA1 mutation and CHEK2 mutation. Invitae genetic testing showed negative for all of these. Living with MBC since 2007. Stopped Herceptin Hylecta (injection) treatment in March 2020. Recent 2023 annual CT of chest, abdomen and pelvis and annual brain MRI showed NED. Praying for NED forever!!