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Yup-- I heard it right: Pre (or peri) menopausal and taking AI's...
Women with infertility issues take AI's -so it is given to premenopausal women. Granted those women are taking the AI for other purposes but taking it nonetheless.
I know there were some italian studies that compared the two in premenopausal women and the results were inconclusive. Another thing- the standard dosage is 20mg and other studies have shown that even 1mg is sufficient. It seems that the dosage amount was an arbitrary amount from the onset of Tamoxifen becoming the gold standard. Yes, it certainly has kept cancer knocked down for so many women, but with the side effects of Tamoxifen, I just wonder why no further study on dosage amounts have been done. This dosage thing has me perplexed- since we now know that other cancer drugs can be overkill as well.
Don't get me wrong- I want to attack this dreaded disease with eveything humanly possible -- and I do not know if taking less Tamoxifen would work.
I will keep looking for answers ...
Maria
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