HER2 Support Group Forums - View Single Post - hopeful case report--letrozole cleared up multiple brain mets

Hopeful · 05-07-2008, 01:09 PM

Gerri,

There have been some study results recently that show that Femara supresses aromatase to a lower level than Arimidex. That said, the difference dosen't seem to be all that much. The action of the two drugs is very similar, though their chemical structures are slightly different (would need to be, for patent purposes anyway). Some patients experience side effects on one drug and not the other. IMO, whichever drug you can tolerate best would be the one to use. FWIW, Femara was initially intended to be taken after Tamoxifen therapy, so you could look up the studies that give the results on that specific protocol for some guidance.

Hopeful

05-07-2008, 01:09 PM	#5
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Gerri, There have been some study results recently that show that Femara supresses aromatase to a lower level than Arimidex. That said, the difference dosen't seem to be all that much. The action of the two drugs is very similar, though their chemical structures are slightly different (would need to be, for patent purposes anyway). Some patients experience side effects on one drug and not the other. IMO, whichever drug you can tolerate best would be the one to use. FWIW, Femara was initially intended to be taken after Tamoxifen therapy, so you could look up the studies that give the results on that specific protocol for some guidance. Hopeful