|
I read the article and ran into the phrase "About one-third of women with HER2 breast cancer develop brain metastases. " Googling for other articles/research seemed to associate ER/PR- HER2+ with the same (so that perhaps ER/PR- negative status is what correlates with the metastases). It was sobering. Will ask my nurse/doctor when I see them next. Research [reported late 2007 and in 2008] seems to indicate that "triple negative" and "ER/PR- HER2" BC's have not as good prognosis. I know I could have this totally wrong and could have misread what I saw. Interestingly enough when I look at the signatures listed on this site...there seems to be some correlation between hormonal status and metastases. [Not statistically valid of course.] If someone knows different I would be glad to hear. Glad though that if this happens something like Tykerb is available. [Not to mention the encouragement found here.]
Melanie
__________________
Diagnosed: 7/13/07 (or 7/7/07)
Surgery: 8/15/07 Modified Radical One Side with Lymph Node Dissection
Pathology Report: ER/PR-, HER2+ with FISH at 8.4 copies, Grade 3, Stage IIIa, 3.2 cm tumor plus 4/19 positive lymph nodes
Portacath: 9/7/07
Chemo: 9/14/07 with AC (every three weeks) for four rounds
Physical Therapy for ROM Loss / "Cording" (but not Lymphodema)
Taxol + Herceptin weekly (started 12/2007 with 8 of 12 Taxol)
Radiation: (28 rads from 3/07 to 4/07)
Reconstruction (silicone implant)
Herceptin done (10/08)
Cognitive Remediation (11/08 - 12/08)
Lymphedema Diagnosed 5/10/10 (almost 3 years post cancer diagnosis)
Lymphedema Rehab 9/10/10 - 11/10/10
Six years NED...7/7/2013!
|