HER2 Support Group Forums - View Single Post

Kristi · 01-18-2008, 04:56 PM

See the winter Cure issue (Vol. 6, No 6) 2007 page 65

"Still it was big new this past summer when two researchers from the Univrsity of Chicago calculated that taking a breast cancer drug with food could save patients and their insurers $1700 per month. The bioavailability of Tykerb increases more than three times when the drug is taken with a highfat meal....Their analysis was based on a pase 1 clinical trial with 27 patients...But don't start cutting your dose. Tykerb's label was written based on phase III clinical trial tests for safety and efficacy...Tyko's manufacturer (says) in early testing, taking the drug with food produced a wide range of bioavailability--some people ended up with much higher blood levels of the drug than others, probably because of different metabolisms and differences in what they eat..."

Thought you all might be interested in this. I just saw it. Kristi

01-18-2008, 04:56 PM	#15
Kristi Member Join Date: Jan 2008 Location: San Francisco Bay Area Posts: 7	Dosage of Tykerb See the winter Cure issue (Vol. 6, No 6) 2007 page 65 "Still it was big new this past summer when two researchers from the Univrsity of Chicago calculated that taking a breast cancer drug with food could save patients and their insurers $1700 per month. The bioavailability of Tykerb increases more than three times when the drug is taken with a highfat meal....Their analysis was based on a pase 1 clinical trial with 27 patients...But don't start cutting your dose. Tykerb's label was written based on phase III clinical trial tests for safety and efficacy...Tyko's manufacturer (says) in early testing, taking the drug with food produced a wide range of bioavailability--some people ended up with much higher blood levels of the drug than others, probably because of different metabolisms and differences in what they eat..." Thought you all might be interested in this. I just saw it. Kristi