HER2 Support Group Forums - View Single Post - The traditional diet of Greece and cancer.

R.B. · 01-09-2008, 05:10 PM

A bit technical but on the same theme that more omega three <img src="http://www.world-of-smilies.com/wos_engel/wos_engell4.gif" alt="Good vs Evil 2" /> and less omega six reduces proliferation and induces cell death between 48-62% in the lab on a particular line of breast cancer cells MDA-MB-231 [A Her2 connected cell line].

LA = linoleic acid an Omega Six

"(a combination of EPA and DHA) inhibited (P < 0.05) the growth of MDA-MB-231 cells by 48-62% in the presence and absence, respectively, of linoleic acid (LA)."

"our results indicate that (n-3) FA modify the lipid composition of membrane rafts and alter EGFR signaling in a way that decreases the growth of breast tumors."

http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum
J Nutr. 2007 Mar;137(3):548-53.Click here to read Links

Comment in:
J Nutr. 2007 Mar;137(3):545-7.

(n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells.
Schley PD, Brindley DN, Field CJ.

Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5.

01-09-2008, 05:10 PM	#14
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	A bit technical but on the same theme that more omega three <img src="http://www.world-of-smilies.com/wos_engel/wos_engell4.gif" alt="Good vs Evil 2" /> and less omega six reduces proliferation and induces cell death between 48-62% in the lab on a particular line of breast cancer cells MDA-MB-231 [A Her2 connected cell line]. LA = linoleic acid an Omega Six "(a combination of EPA and DHA) inhibited (P < 0.05) the growth of MDA-MB-231 cells by 48-62% in the presence and absence, respectively, of linoleic acid (LA)." "our results indicate that (n-3) FA modify the lipid composition of membrane rafts and alter EGFR signaling in a way that decreases the growth of breast tumors." http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum J Nutr. 2007 Mar;137(3):548-53.Click here to read Links Comment in: J Nutr. 2007 Mar;137(3):545-7. (n-3) PUFA alter raft lipid composition and decrease epidermal growth factor receptor levels in lipid rafts of human breast cancer cells. Schley PD, Brindley DN, Field CJ. Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5.