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Old 01-08-2008, 08:50 AM   #1
alw
Senior Member
 
Join Date: Apr 2006
Posts: 63
Cytogenetic analysis of HER1/EGFR, HER2, HER3, AND HER4 in 278 breast cancer patients

http://breast-cancer-research.com/content/pdf/bcr1843.pdf
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Amy age 37 at dx
Feb 2008 Multifocal DCIS
Apr 2008 Bilateral Mastectomies

Sister to Laura age 37 at dx
April 2006
9 cm ER-/PR- Her2 +++/bone mets
neoadjuvant TCH plus Zometa
November 2006
bilateral mastectomy - Change to ER+/PR- Her2 +++
January 2007
innumerable tiny brain mets - WBR
March 2007
good response to WBR - some gone, all smaller
currently on Lapatinib and Xeloda
Feb 2008
Brain MRI: brain mets went from innumerable (jan '07) to 5 (june '07) to 3 (oct '07) to 1 that is getting less conspicuous(feb '08) PET/CT: Slight uptake in some sclerotic bone mets
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