HER2 Support Group Forums - View Single Post - Speaking of tumor markers: Osteopontin-C

Hopeful · 11-07-2007, 07:47 PM

Grace,

I found the link to the abstract that this article was based on:http://www3.interscience.wiley.com/c...34104/ABSTRACT

It states, "Osteopontin-c is selectively expressed in invasive, but not in noninvasive, breast tumor cell lines, and it effectively supports anchorage independence."

From reading the sentence above, I take it this marker is only useful for invasive cancer. I can't think of what invasive cancer would not require surgery - may be a mistake in the quote.

Hopeful

11-07-2007, 07:47 PM	#4
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Grace, I found the link to the abstract that this article was based on:http://www3.interscience.wiley.com/c...34104/ABSTRACT It states, "Osteopontin-c is selectively expressed in invasive, but not in noninvasive, breast tumor cell lines, and it effectively supports anchorage independence." From reading the sentence above, I take it this marker is only useful for invasive cancer. I can't think of what invasive cancer would not require surgery - may be a mistake in the quote. Hopeful