Translational studies on aromatase, cyclooxygenases, and enzyme inhibitors in breast cancer.
Brueggemeier RW, DÃ*az-Cruz ES, Li PK, Sugimoto Y, Lin YC, Shapiro CL.
College of Pharmacy, The Ohio State University, 500 W. 12th Avenue, Columbus, OH 43210, USA.
brueggemeier.1@osu.edu
"In summary, pharmacological regulation of aromatase and cyclooxygenases can act locally in an autocrine fashion to decrease the biosynthesis of estrogen and may provide additional therapy options for patients with hormone-dependent breast cancer."