HER2 Support Group Forums - View Single Post - The traditional diet of Greece and cancer.

R.B. · 11-01-2007, 06:58 PM

Omega six in vegetable oils in your diet is converted to arachidonic acid `AA' a member of the omega six family.

AA is converted by COX2 to products that show a relationship to breast and other cancers. The amount of these COX products your body produces is a function of how much omega six you eat. These products include the sex hormones through the aromatase pathways.

Omega three competes for and blocks conversion of AA by COX.

So the amount of omega three and six in your diet can impact on the COX2 pathways, and downstream direct or indirect products, including hormones.

RB

http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum

COX-2 expression in invasive breast cancer: correlation with prognostic parameters and outcome.
Nassar A, Radhakrishnan A, Cabrero IA, Cotsonis G, Cohen C.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA. anassar@emory.edu

"COX-2 expression is also associated with increased angiogenesis, lymph node metastasis, and Her2-neu overexpression. ". . . "In conclusion, COX-2 correlates with poor prognostic markers in breast cancer (large tumor size and high tumor grade), but not with outcome.". . .

11-01-2007, 06:58 PM	#170
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	COX-2 expression in invasive breast cancer: correlation with outcome Omega six in vegetable oils in your diet is converted to arachidonic acid `AA' a member of the omega six family. AA is converted by COX2 to products that show a relationship to breast and other cancers. The amount of these COX products your body produces is a function of how much omega six you eat. These products include the sex hormones through the aromatase pathways. Omega three competes for and blocks conversion of AA by COX. So the amount of omega three and six in your diet can impact on the COX2 pathways, and downstream direct or indirect products, including hormones. RB http://www.ncbi.nlm.nih.gov/sites/en...ubmed_RVDocSum COX-2 expression in invasive breast cancer: correlation with prognostic parameters and outcome. Nassar A, Radhakrishnan A, Cabrero IA, Cotsonis G, Cohen C. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA. anassar@emory.edu "COX-2 expression is also associated with increased angiogenesis, lymph node metastasis, and Her2-neu overexpression. ". . . "In conclusion, COX-2 correlates with poor prognostic markers in breast cancer (large tumor size and high tumor grade), but not with outcome.". . .