HER2 Support Group Forums - View Single Post - The traditional diet of Greece and cancer.

R.B. · 10-23-2007, 03:51 PM

Thank you for the kind thought and encouragement AndiBB.

This trial result is intriguing in that it suggests the body may increase COX2 in response to an omega 3 shortage.

COX2 is the substance COX blocking drugs target.

The probable consequences of this in a high omega six world would be that the conversion ability of omega six products to the inflammatory chemicals including PGE2 would be increased.

COX2 is the substance used by the omega sixes to make the omega six family of inflammatory chemicals.

So another straw in the breeze that it is a sensible risk reduction strategy to balance omega three and six intake (as well as reducing the risk of bipolar disorder).

http://www.nature.com/mp/journal/v12.../4001887a.html

Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex

J S Rao1, R N Ertley1, J C DeMar Jr1, S I Rapoport1, R P Bazinet1 and H-J Lee1

Abstract

The finding that n-3 PUFA deprivation increases cPLA2, sPLA2 and COX-2 is opposite to what has been reported after chronic administration of anti-manic agents to rats and suggests that n-3 PUFA deprivation may increase susceptibility to bipolar disorder.

10-23-2007, 03:51 PM	#12
R.B. Senior Member Join Date: Mar 2006 Posts: 1,843	Thank you for the kind thought and encouragement AndiBB. This trial result is intriguing in that it suggests the body may increase COX2 in response to an omega 3 shortage. COX2 is the substance COX blocking drugs target. The probable consequences of this in a high omega six world would be that the conversion ability of omega six products to the inflammatory chemicals including PGE2 would be increased. COX2 is the substance used by the omega sixes to make the omega six family of inflammatory chemicals. So another straw in the breeze that it is a sensible risk reduction strategy to balance omega three and six intake (as well as reducing the risk of bipolar disorder). http://www.nature.com/mp/journal/v12.../4001887a.html Dietary n-3 PUFA deprivation alters expression of enzymes of the arachidonic and docosahexaenoic acid cascades in rat frontal cortex J S Rao1, R N Ertley1, J C DeMar Jr1, S I Rapoport1, R P Bazinet1 and H-J Lee1 Abstract The finding that n-3 PUFA deprivation increases cPLA2, sPLA2 and COX-2 is opposite to what has been reported after chronic administration of anti-manic agents to rats and suggests that n-3 PUFA deprivation may increase susceptibility to bipolar disorder.