HER2 Support Group Forums - View Single Post - I thought I was crazy when I noticed a seasonality to bc metastases

Lani · 10-16-2007, 01:00 PM

clearly there is some "clock mechanism" as tumors tend to recur in peaks
a certain number of months after surgery (not after lumps discovered) and the certain number of months differs by tumor subtype, at least w her2neu
the initial peak occurs 24-36 months or so after surgery as I understand it.

Circadian rhythm research is not well funded and research on melatonin is not very advanced at present it seems....

10-16-2007, 01:00 PM	#4
Lani Senior Member Join Date: Mar 2006 Posts: 4,778	also perhaps an effect of vitamin D clearly there is some "clock mechanism" as tumors tend to recur in peaks a certain number of months after surgery (not after lumps discovered) and the certain number of months differs by tumor subtype, at least w her2neu the initial peak occurs 24-36 months or so after surgery as I understand it. Circadian rhythm research is not well funded and research on melatonin is not very advanced at present it seems....