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Dear Alice
KI 67 measures how fast the cancer cells are reproducing. Most Her2+ cancers reproduce fast. The higher the % the faster it is reproducing.
P53 is the tumor suppressor gene. I am not sure what is measured. Mine was 10% and my mom's was less than 5%. I think it measures how many cells have a mutated p53.
Do not think about prognosis. Chemo kills cells that are rapidly reproducing. Prognosis is still "measured" prior to good chemo regimes and adjuvant Herceptin.
Feel well, smile and put the pathology report back in your file where it belongs and have a nice weekend.
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Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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