[Lani]

in Spain they are doing a trial with Herceptin and Pertuzumab reported by Dr. Baselga at ASCO ( I watched the virtual meeting last night)

The biggest news is a paper authored by Kent Osborne and Rachael Schiff of Baylor where they were able to cure her2+ bc in mice with herceptin, pertuzumab and Iressa (like Tykerb, but blocks only her1 aka EGFR)

Tarceva, a similar oral EGFR tyrosine kinase inhibitor, is approved for other purposes, I believe --it is just pertuzumab we are waiting for.

There are papers about other drugs which improve the efficacy of Herceptin including fluvastatin and Velcade (approved for multiple myeloma)

In prostate cancer a combination of a very high dose (given in a dosing pattern to avoid kidney stones) vitamin D and Aleve was very effective in metastatic prostate cancer and they were to begin a similar clinical trial in breast cancer at Stanford (don't know if paperwork still in progress or approved)

Just throwing things out there as what you asked for was hope.

Now Becky's suggestions are much more practical and down to earth.

Hope both benefit you!