HER2 Support Group Forums - View Single Post - Desperate for hope: anyone er-, pr+, HER2+++ but nonresponsive to Herceptin/Tykerb?

Becky · 07-12-2007, 08:06 PM

Try the Faslodex and Aromosin. You may be ER+ as your cancer changed to PR+ along the way. It certainly can help. Secondly, weekly Abraxane with Herceptin and Tykerb are worth a shot. Maybe your onc will give you Tykerb with the Herceptin. If not, try the Abraxane with Herceptin (along with Faslodex and Aromosin). You may get enough of a response to be well enough to find a trial. See if your onc (if adverturous) will try Tykerb with that mix too. It is a Her1 and 2 blocker.

I will see if there are any trials but all these drugs are approved. Call tomorrow so you can get dosed right away and chase those mets away.

07-12-2007, 08:06 PM	#7
Becky Senior Member Join Date: Sep 2005 Location: Stockton, NJ Posts: 4,179	Try the Faslodex and Aromosin. You may be ER+ as your cancer changed to PR+ along the way. It certainly can help. Secondly, weekly Abraxane with Herceptin and Tykerb are worth a shot. Maybe your onc will give you Tykerb with the Herceptin. If not, try the Abraxane with Herceptin (along with Faslodex and Aromosin). You may get enough of a response to be well enough to find a trial. See if your onc (if adverturous) will try Tykerb with that mix too. It is a Her1 and 2 blocker. I will see if there are any trials but all these drugs are approved. Call tomorrow so you can get dosed right away and chase those mets away. __________________ Kind regards Becky Found lump via BSE Diagnosed 8/04 at age 45 1.9cm tumor, ER+PR-, Her2 3+(rt side) 2 micromets to sentinel node Stage 2A left 3mm DCIS - low grade ER+PR+Her2 neg lumpectomies 9/7/04 4DD AC followed by 4 DD taxol Used Leukine instead of Neulasta 35 rads on right side only 4/05 started Tamoxifen Started Herceptin 4 months after last Taxol due to trial results and 2005 ASCO meeting & recommendations Oophorectomy 8/05 Started Arimidex 9/05 Finished Herceptin (16 months) 9/06 Arimidex Only Prolia every 6 months for osteopenia NED 18 years! Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"