[Joy]

I am a xeloda 2-timer. When I was first diagnosed with terrible liver mets, possible lung mets I did xeloda, taxotere and herceptin and had great response. That was five years ago. Now I am on xeloda/tykerb and we think it is working. We will know more at the end of the month and i will definitely post the results whatever they may be. My oncologist whom/who (?) I like and trust very much (and I am a questioner/researcher) said that the "rule" is you can repeat chemos (again choosing them is an art) after approximately 2 years. Now, of course, will they work? Yes, sometimes they do and do quite well. As with any cancer treatment there are regimens that work and don't work depending on the individual.

Also, when i stopped xeloda/taxotere after 9 months because the tumors were eliminated or tiny and I went to a hormonal treatment it was determined that I had not grown resistant, we just stopped. So I think that can be factor, too.

I hope others respond to yur post and encourage you in your treatment decisions. A second opinion is always a healthy, responsible thing and the internet can provide you with studies regarding sequencing of treatments.

Please let us know what you find out and how you are doing and know we are thinking of you.