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chrisy · 06-20-2007, 03:25 PM

Hi Barbara,
I'm sure you are very discouraged right now. You are probably right about the trial, and may also have to stop Herceptin for a while to let your heart rebound. The good news is, most times the damage is reversible and after coming off Herceptin for a time, people can go back on again. Keep in mind, this is for your protection - none of this will do any good if you don't have a beating heart.

Couple of things to consider, tho - have you had ECHO's or MUGA's in the past? And if so, is this result appreciably different from your prior? Perhaps you could get it "redone". I've had mine fluctuate to as low as 53 then up to 68. I just had an ECHO yesterday - so of course I've got that top of mind myself.

As to how to get things back on track, here is a link Becky posted regarding aerobic training, and I know many have taken CoQ10 supplements to support their heart health.
http://her2support.org/vbulletin/sho...light=ejection

06-20-2007, 03:25 PM	#2
chrisy Senior Member Join Date: Sep 2005 Location: Central Coast, CA Posts: 3,207	Hi Barbara, I'm sure you are very discouraged right now. You are probably right about the trial, and may also have to stop Herceptin for a while to let your heart rebound. The good news is, most times the damage is reversible and after coming off Herceptin for a time, people can go back on again. Keep in mind, this is for your protection - none of this will do any good if you don't have a beating heart. Couple of things to consider, tho - have you had ECHO's or MUGA's in the past? And if so, is this result appreciably different from your prior? Perhaps you could get it "redone". I've had mine fluctuate to as low as 53 then up to 68. I just had an ECHO yesterday - so of course I've got that top of mind myself. As to how to get things back on track, here is a link Becky posted regarding aerobic training, and I know many have taken CoQ10 supplements to support their heart health. http://her2support.org/vbulletin/sho...light=ejection __________________ Chris in Scotts Valley June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?" 9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++ 10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response! 04/05 - 4/07 Herception every 3 wks, Continue NED 04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial 06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin 01/08 Progression in liver 02/08 Begin (TDM1) trial 08/08 NED! It's Working! Continue on TDM1 02/09 Continue NED 02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED 12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver 07/11 - 11/11 Herceptin/Xeloda -not working:( 12/11 Begin MM302 Phase I trial - bust:( 03/12 3rd times the charm? AKT trial 5/12 Scan shows reduction! 7/12 More reduction!!!! 8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!) 9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3 11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc 11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go. 2/13 Gemzar/Carbo/Herceptin - no go. 3/13 TACE procedure