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Lolly · 06-13-2007, 08:39 PM

Just wanted to post my Echo results after a month on Tykerb and two months off Herceptin: my LVEF is 65%!
Last year my Muga came in at 49%, the lowest since starting Herceptin in 2001. The number has been slowly but surely declining over the years, so when my onc ordered the Echo after our last visit when I complained of tiredness(red counts are decent), I was a bit worried that Tykerb was affecting my heart function and dropping it even lower...NOT SO! My heart has bounced back and I'm so relieved!

Just wanted you all to know, who may be worried about Tykerb affecting the LVEF, it ain't necessarily so!

<3 Lolly

06-13-2007, 08:39 PM	#1
Lolly Senior Member Join Date: Aug 2001 Location: Oregon Posts: 1,756	Heart doing GREAT on Tykerb Just wanted to post my Echo results after a month on Tykerb and two months off Herceptin: my LVEF is 65%! Last year my Muga came in at 49%, the lowest since starting Herceptin in 2001. The number has been slowly but surely declining over the years, so when my onc ordered the Echo after our last visit when I complained of tiredness(red counts are decent), I was a bit worried that Tykerb was affecting my heart function and dropping it even lower...NOT SO! My heart has bounced back and I'm so relieved! Just wanted you all to know, who may be worried about Tykerb affecting the LVEF, it ain't necessarily so! <3 Lolly __________________ Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation. Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.