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Val Pfeiffer · 03-16-2007, 05:16 AM

Joe--
I thought of a couple things to ask--maybe they're repetitive, so my apologies (I only have a moment this monring).

1. Please comment on the preventative properties of Tykerb with respect to brain mets. Do they feel there is value in taking the drug in situations where there is a high probability of brain mets?

2. Please comment on the value of Tykerb when taken by iteself. What do you feel that the difference in Tykerb's efficacy when (1) taken by itself, and (2) combined with other drugs (which ones)?

thanks!
Val

03-16-2007, 05:16 AM	#30
Val Pfeiffer Senior Member Join Date: Feb 2005 Location: Wisconsin Posts: 159	Joe-- I thought of a couple things to ask--maybe they're repetitive, so my apologies (I only have a moment this monring). 1. Please comment on the preventative properties of Tykerb with respect to brain mets. Do they feel there is value in taking the drug in situations where there is a high probability of brain mets? 2. Please comment on the value of Tykerb when taken by iteself. What do you feel that the difference in Tykerb's efficacy when (1) taken by itself, and (2) combined with other drugs (which ones)? thanks! Val __________________ BLOG: http://valleygirlvnp.blogspot.com/ Dx 11/04, Age 42, ER-/PR-, HER2+++ 3 months weekly Herceptin, Taxol. Carboplatin Significant tumor shrinkage Mastectomy 3/05; Stage 3b, 9 cm tumor, 5/8+ nodes 3 more months weekly Herceptin, Taxol. Carboplatin 7/05 30 radiation treatments, IMRT planning approach Started 1 year of Herceptin 9/05 9/06 Began quarterly triple doses Herceptin. Brain & breast MRIs semi annually. * * * * * * * * * * * * * * * * * * * * * * * * * * * 6/08 Right breast, intraductal carcinoma, high nuclear grade associated with comedo necrosis; extensive diffusely involved the entire biopy specimen. ER+, PR-, Her2 unknown at this point, 07/08 mastectomy.