HER2 Support Group Forums - View Single Post - Expert interview:Gene-Expression Signatures -Clinical Implications for Breast Cancer

AlaskaAngel · 02-01-2007, 01:13 PM

That pretty much leaves most HER2's in no-person's-land, because the TAILOR-X trial specifically excludes HER2 positives. There is also a conspicious lack of any discussion about the use of Oncotype Dx for those HR+ HER2 positives who did go through chemo to provide any direction for further treatment. And much of the comments I've seen here about the use of Oncotype Dx prior to treatment indicate that anyone who is considered really HER2 positive is pretty much automatically recommended to have chemo. So TAILOR-X and Oncotype Dx don't do much for us, although hopefully they will help some who aren't HER2 positive.

AlaskaAngel

02-01-2007, 01:13 PM	#6
AlaskaAngel Senior Member Join Date: Sep 2005 Location: Alaska Posts: 2,018	HER2 positives That pretty much leaves most HER2's in no-person's-land, because the TAILOR-X trial specifically excludes HER2 positives. There is also a conspicious lack of any discussion about the use of Oncotype Dx for those HR+ HER2 positives who did go through chemo to provide any direction for further treatment. And much of the comments I've seen here about the use of Oncotype Dx prior to treatment indicate that anyone who is considered really HER2 positive is pretty much automatically recommended to have chemo. So TAILOR-X and Oncotype Dx don't do much for us, although hopefully they will help some who aren't HER2 positive. AlaskaAngel