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Heblaj01.
Obviously busy extensively reading, and through too. Impressed.
I have not had time to do more that a 5 minute skim but in trying t find the full trial on the DNA damage I did find this which was thought provoking.
The bit I found intriguing was the recovery of cells in 120 minutes. Does this apply to both normal and cancercous cells or do cells recover differently?
It seems like many food it has its pluses and minues which brings one back to the issue of as wider a possible variety wich applies both to what we eat and the things we eat have eaten.
RB
Abstract
Department of Molecular Genetics, University of Lodz, Lodz, Poland.
The naturally occurring pigment curcumin, a major component of the spice turmeric, is reported to be a potent inhibitor of the initiation and promotion of many cancers. Due to its presence in the diet, one of its primary targets is the human gastric mucosa (GM) cells. Using the sensitive single cell electrophoresis method (comet assay), we found that curcumin at of 15, 25, and 50 microM caused DNA damage in GM cells and human peripheral blood lymphocytes. There was no difference between the extent of the damage in both types of cells. Damaged cells were able to recover within a period of 120 minutes. Our results indicate that curcumin may play a dual role in carcinogenesis.
PMID: 15281237 [PubMed - indexed for MEDLINE]
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