HER2 Support Group Forums - View Single Post - BREAST CANCER UPDATE 7 of 2006:expert interviews

Christine MH-UK · 12-11-2006, 12:09 PM

Pegram made a few points that I found interesting in his track on FinHer:
1) All of the herceptin trials had been 'massively overpowered,' i.e. they did not need to be nearly as big as they were.
2) The HERA 2 year arm results are expected out in 2008 (this seems to get perpetually pushed back, which does not seem encouraging). If the 2 year arm proves to be more effective than the 1 year arm, they will not try shorter courses. If the 2 year arm is no better, only then will they try shorter courses. I find it disconcerting that the results announcement date keeps on getting pushed back farther and farther.

12-11-2006, 12:09 PM	#2
Christine MH-UK Senior Member Join Date: Sep 2005 Posts: 414	Great Find Pegram made a few points that I found interesting in his track on FinHer: 1) All of the herceptin trials had been 'massively overpowered,' i.e. they did not need to be nearly as big as they were. 2) The HERA 2 year arm results are expected out in 2008 (this seems to get perpetually pushed back, which does not seem encouraging). If the 2 year arm proves to be more effective than the 1 year arm, they will not try shorter courses. If the 2 year arm is no better, only then will they try shorter courses. I find it disconcerting that the results announcement date keeps on getting pushed back farther and farther.