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Hopeful · 10-19-2006, 06:50 AM

Lani, Here is a link to the article by Sorlie referred to in the article you posted about 16q: http://www.pnas.org/cgi/content/full/98/19/10869 This was one of the earlier articles I read about gene patterns and bc. I am still a bit confused by their classification of Luminal B and Luminal C; they seem to lump them together sometimes, and other times distinguish them as separate groups. It also shows the Luminal B's bouncing around on the graphs where they do their gene groupings. If you have an interpretation of this characterization, I would be most interested in reading it, as you seem to have an excellent grasp on all of the molecular biology issues.

thanks,

Hopeful

10-19-2006, 06:50 AM	#80
Hopeful Senior Member Join Date: Aug 2006 Posts: 3,380	Luminals Lani, Here is a link to the article by Sorlie referred to in the article you posted about 16q: http://www.pnas.org/cgi/content/full/98/19/10869 This was one of the earlier articles I read about gene patterns and bc. I am still a bit confused by their classification of Luminal B and Luminal C; they seem to lump them together sometimes, and other times distinguish them as separate groups. It also shows the Luminal B's bouncing around on the graphs where they do their gene groupings. If you have an interpretation of this characterization, I would be most interested in reading it, as you seem to have an excellent grasp on all of the molecular biology issues. thanks, Hopeful