Carina -
I am in the process of trying to get into the Tykerb clinical trial for pre-mets bc patients who are 8 years or less out of chemo. It is my understanding though that one of the requirements is that you have never received herceptin.
Here's a link to the clinical trial info. If you scroll down it lists contacts in Canada, I think there are some centers in Toronto listed.
http://www.clinicaltrial.gov/ct/show...00D87?order=16
Take care,
Pat