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Search: Posts Made By: Nguyen
Forum: Articles of Interest 07-19-2020, 03:22 PM
Replies: 0
Views: 217
Posted By Nguyen
Six distinct "types" of COVID-19 identified

A bit "dramatized title" in the simplified version, note information have not been through peer reviewed process.

Nguyen

The simplified version:
...
Forum: Articles of Interest 07-17-2020, 07:01 PM
Replies: 0
Views: 106
Posted By Nguyen
Metastatic HER2+ Breast Cancer Treatment Must Move to Personalized Approach

https://www.onclive.com/view/metastatic-her2-breast-cancer-treatment-must-move-to-personalized-approach
Forum: Articles of Interest 07-17-2020, 06:49 PM
Replies: 0
Views: 92
Posted By Nguyen
Leveraging CDK4/6 Inhibitors in Earlier Settings to Boost Outcomes in HR+ Breast Canc

https://www.onclive.com/view/leveraging-cdk4-6-inhibitors-in-the-earlier-settings-to-boost-outcomes-in-hr-breast-cancer
Forum: Articles of Interest 07-17-2020, 01:02 PM
Replies: 0
Views: 99
Posted By Nguyen
Risk of early progression according to circulating ESR1 mutation...

https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-020-01290-x

Abstract
Background

Endocrine therapy is recommended as a first-line treatment for hormone...
Forum: her2group 07-11-2020, 08:52 AM
Replies: 1
Views: 370
Posted By Nguyen
Re: Abemaciclib plus trastuzumab with or without fulvestrant versus trastuzumab plus

Thanks Lani, somehow I missed this. This info has immediate use for us in our upcoming treatment decision, assuming we can get it via off-label used for her2 positive.

Nguyen
Forum: Articles of Interest 06-25-2020, 08:28 PM
Replies: 0
Views: 299
Posted By Nguyen
Hopefully this will be another weapon for us in the fight.

https://www.icr.ac.uk/news-archive/new-class-of-precision-medicine-strips-cancer-of-its-dna-defences


https://ascopubs.org/doi/10.1200/JCO.19.02404
Forum: Articles of Interest 06-25-2020, 07:26 AM
Replies: 0
Views: 118
Posted By Nguyen
Cardiac monitoring in HER2-positive patients

Cardiac monitoring in HER2-positive patients on trastuzumab treatment: A review and implications for clinical practice
...
Forum: Articles of Interest 06-11-2020, 09:58 AM
Replies: 0
Views: 203
Posted By Nguyen
6/2020:American Cancer Society Guideline for Diet and Physical Activity for cancer pr

If memory serves, main difference with past recommendations is double the amount of daily exercise and intensity.

Nguyen

https://acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/caac.21591...
Forum: Articles of Interest 06-08-2020, 07:34 AM
Replies: 0
Views: 168
Posted By Nguyen
A couple of articles on current immunotherapy for her2 positive BC

Useful background info, albeit a bit long and moderately technical, note "current" <= 03/2020.

Nguyen

https://www.nature.com/articles/s41523-020-0153-3
...
Forum: Articles of Interest 06-05-2020, 09:28 AM
Replies: 1
Views: 236
Posted By Nguyen
Re: Treatment After Progression on CDK 4/6i in mBC

Therapy After Cyclin-Dependent Kinase Inhibition in Metastatic
Hormone Receptor-Positive Breast Cancer: Resistance
Mechanisms and Novel Treatment Strategies
...
Forum: Articles of Interest 05-29-2020, 03:52 PM
Replies: 0
Views: 335
Posted By Nguyen
Tucatinib aka ONT-380

After more than 20+ years ...

https://www.onclive.com/web-exclusives/tucatinib-lead-researcher-explains-significance-of-fda-approval-in-her2-positive-breast-cancer?p=1
...
Forum: Articles of Interest 05-29-2020, 03:37 PM
Replies: 1
Views: 236
Posted By Nguyen
Treatment After Progression on CDK 4/6i in mBC

Not really appropriate title, but there are useful info in it.

Nguyen
...
Forum: Articles of Interest 05-29-2020, 09:00 AM
Replies: 0
Views: 215
Posted By Nguyen
COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the P

https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-020-01293-8

Abstract
Background

Cancer patients have been reported to be at higher risk of COVID-19 complications and...
Forum: Articles of Interest 05-24-2020, 09:20 PM
Replies: 0
Views: 189
Posted By Nguyen
Trastuzumab Deruxtecan Shows Efficacy in HER2+ Breast Cancer Brain Mets

https://www.onclive.com/conference-coverage/esmo-breast-2020/trastuzumab-deruxtecan-shows-efficacy-in-her2-positive-breast-cancer-brain-mets?eKey=RGFkYUFrYUF1c3RpbkRhZEBnbWFpbC5jb20=
Forum: Articles of Interest 04-29-2020, 10:50 AM
Replies: 0
Views: 419
Posted By Nguyen
Discordance in ER/PR/Her2 ; Imaging to detect Hormone Receptor

In the “old” way of doing thing, when primary and met sites were treated as only two “clumps”, the discordant rates between the two were about 17% for er/pr and 8% for her2. With newer technology,...
Forum: Articles of Interest 04-21-2020, 07:48 AM
Replies: 3
Views: 646
Posted By Nguyen
Re: Perhaps something we can do in case we can't get treatment for covid-19.

https://www.nytimes.com/2020/04/20/opinion/coronavirus-testing-pneumonia.html

The above article is along what I posted earlier, but more deterministic. I suggest read comments by other Md's...
Forum: Articles of Interest 04-20-2020, 09:04 AM
Replies: 0
Views: 236
Posted By Nguyen
Vision problems due to anastrozole, bisphosphonate, or ???

My wife vision suddenly (in about 2-3 months time frame) got worse by 3+ diopters. In researching causes, I found the below articles, which might be of interest.

Nguyen
...
Forum: Articles of Interest 04-17-2020, 06:48 AM
Replies: 2
Views: 389
Posted By Nguyen
Forum: Articles of Interest 04-11-2020, 07:47 AM
Replies: 3
Views: 646
Posted By Nguyen
Perhaps something we can do in case we can't get treatment for covid-19.

We were sad and worry after stumbling across a triage list in our state regarding medical resources (device and treatment), it is not surprising to see metastatic cancer patients make the exclusion...
Forum: Articles of Interest 04-11-2020, 07:41 AM
Replies: 2
Views: 389
Posted By Nguyen
A few words about N95 respirator

I thought I write a few words about N95 mask, sorry if this information are trivial to you. if you are next to someone wearing an N95 mask with valve (the respirator has a protruding mechanism on...
Forum: Articles of Interest 04-07-2020, 07:43 PM
Replies: 0
Views: 274
Posted By Nguyen
In case you are making a mask.

Hello, I am not sure if this thread belong here, feel free to move where ever appropriate. PM for bigger images. Thanks.

- Nguyen

Disposable surgical type mask

Material: 8x11 paper, napkin...
Forum: Articles of Interest 04-01-2020, 01:03 PM
Replies: 1
Views: 377
Posted By Nguyen
A few Covid-19 and cancer articles

https://jamanetwork.com/journals/jamaoncology/fullarticle/2763961?guestAccessKey=ae55ef43-a2a2-40f7-8976-8aa2ce73926b&utm_source=silverchair&utm_medium=email&utm_campaign=article_alert-jamaoncology&ut...
Forum: her2group 02-11-2020, 11:55 AM
Replies: 2
Views: 497
Posted By Nguyen
For early stage bc, how are you being monitored?

Hello,

If you are at stage 0 or 1, what method (tumor marker, imaging, clinical exam, or ???) and frequency (quarterly, semi-annually, annually, or ???) are used to monitor for relapse?

Thanks,...
Forum: Articles of Interest 02-10-2020, 12:33 PM
Replies: 0
Views: 345
Posted By Nguyen
Personalized Detection of Circulating Tumor DNAAntedates Breast Cancer Metastatic Rec

I might have posted this already.

https://clincancerres.aacrjournals.org/content/clincanres/25/14/4255.full.pdf

AbstractPurpose:Up to 30% of patients with breast cancer relapseafter primary...
Forum: Articles of Interest 02-09-2020, 06:35 PM
Replies: 0
Views: 323
Posted By Nguyen
Efficacy and Safety of Nab-Paclitaxel Compared With Solvent-Based Taxanes for Metasta

https://www.practiceupdate.com/c/95456/67/13/?elsca1=emc_enews_weekinreview&elsca2=email&elsca3=practiceupdate_metastaticbreastcancer&elsca4=metastaticbreastcancer&elsca5=newsletter&rid=NjIyODUwOTM0ND...
Showing results 1 to 25 of 249

 
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