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Forum: Herceptin / Tykerb

12-06-2008, 04:27 PM

Replies: 12

Tykerb side effects??? Help, please

Views: 4,602

Posted By donocco5w4

Adriana I did some research at the City of...

Adriana

I did some research at the City of Hope Library on Tykerb Acne. The lesions look very similar to acne but there are differences, mainly with Tykerb acne there are no blackheads...

Forum: Articles of Interest

12-02-2008, 01:47 PM

Replies: 4

Valproic acid against er+ cancer (from top 5 list)

Views: 1,413

Posted By donocco5w4

I have been interested in the Histone deacetylase...

I have been interested in the Histone deacetylase action of Valproic Acid for years. This action of Vaproic acid is rarely mentioned in my pharmacy textbooks and as the drug penetrates the blood...

Forum: her2group

11-24-2008, 12:27 PM

Replies: 41

Anyone Heard Of: "REXIN-G"???

Views: 8,441

Posted By donocco5w4

I did some research on Rexin G. The info is...

I did some research on Rexin G. The info is complicated and involves understanding the interaction between Cyclin G1, a protein called ARF and another protein Called MDM2. Apparently ARF and MDM2 act...

Forum: her2group

11-03-2008, 01:23 PM

Replies: 28

Bisphosphonates as preventative

Views: 3,930

Posted By donocco5w4

Forteo really isnt a long acting Biphosphonate....

Forteo really isnt a long acting Biphosphonate. It is a synthetic parathyroid hormone deriviative. Biphosphanates work by decreasing Osteoclast activity. The osteoclasts are the bone cells that break...

Forum: her2group

10-13-2008, 11:29 PM

Replies: 2

antidepressant ?

Views: 1,418

Posted By donocco5w4

Pristiq is Desvenlafaxine, very similar to...

Pristiq is Desvenlafaxine, very similar to Venlafaxine (Effexor). It differs from Zoloft in that it inhibits the reuptake of both Serotonin and Norepinephrine. Zoloft only inhibits Serotonin...

Forum: General Cancer News

10-12-2008, 01:57 PM

Replies: 1

Painkillers found to reduce breast cancer risk

Views: 964

Posted By donocco5w4

I remember reading an article in the American...

I remember reading an article in the American Journal of Epidemiology way back in the 1990s that compared the breast cancer rates of women who took a few Ibuprofen (motrin) tablets a week vs those...

Forum: her2group

10-10-2008, 09:48 PM

Replies: 10

Question....CoQ-10

Views: 1,336

Posted By donocco5w4

In the 1990's there was a report of 4 metastatic...

In the 1990's there was a report of 4 metastatic breast cancer patients taking 390mg Q 10 daily (they were also on chemo) and the mets disappeared. I dont know what to make of this but who knows?....

Forum: her2group

07-11-2008, 10:53 AM

Replies: 5

oncologists' practices "hurting" per Wall St. Journal

Views: 1,359

Posted By donocco5w4

Run I know my knowledge of...

Run

I know my knowledge of pharmacoeconomics is simplistic but I "picked on" Sutent for a reason. In one experiment with a transplanted pancreatic tumour in mice combinations of Varying dosing...

Forum: her2group

07-08-2008, 01:08 PM

Replies: 5

oncologists' practices "hurting" per Wall St. Journal

Views: 1,359

Posted By donocco5w4

I remember when I had my own pharmacy and the...

I remember when I had my own pharmacy and the drug Mevacor was approved. Mevacor was the first of the anti-cholesteral statin drugs to be aproved and Lipitor is a more modern Statin drug.This was in...

Forum: Articles of Interest

07-07-2008, 07:10 PM

Replies: 2

Vitamin D receptor variant linked to early onset breast cancer

Views: 1,116

Posted By donocco5w4

There was a question about Vitamin D...

There was a question about Vitamin D supplemantation from another group. The womans oncologist prescribed her 50,000 units Vitamin D weekly as her Vitamin D level came back too low and she asked me...

Forum: Articles of Interest

05-28-2008, 11:47 PM

Replies: 3

Lipophilic statins protect against breast cancer recurrence

Views: 1,386

Posted By donocco5w4

The Statin Drugs lower blood cholesterol by...

The Statin Drugs lower blood cholesterol by interfering with the production of mevalonic Acid the first step in cholesterol biosynthesis. Lipophilic means fat soluble as opposed to hydrophilic or...

Forum: her2group

05-10-2008, 10:51 PM

Replies: 7

first there was Tiptoe, now there is Dachsund!!

Views: 1,269

Posted By donocco5w4

Interleukin 8 is one of many cyokines. apparently...

Interleukin 8 is one of many cyokines. apparently it is necessary or involved in the metastasis of breast cancer cells. apparently this Dasch gene protein inhibits metastasis by inhibiting the action...

Forum: Articles of Interest

12-28-2007, 02:47 AM

Replies: 4

Celecoxib blocks morphine-induced tumor growth in mice

Views: 1,170

Posted By donocco5w4

Morphine and tumour growth

Its not so much that Morphine stimulates tumour growth, but the bodies natural opiates, the Endorphins can act as immunosuppressants and stimulate tumour growth. Both the action of Morphine and the...

Forum: her2group

11-18-2007, 11:12 AM

Replies: 22

Anyone else can't get QUININE for leg cramps??

Views: 4,633

Posted By donocco5w4

quinine Sulfate

I didnt know that but it doesnt surprise me. Since it appears Stephanie lives in Seattle Wa going to Victoria British Columbia would be very easy. It would be possible to open a capsule an d only use...

Forum: her2group

11-18-2007, 03:38 AM

Replies: 22

Anyone else can't get QUININE for leg cramps??

Views: 4,633

Posted By donocco5w4

Quinine for leg cramps

My name is Paul and am the pharmacist in California Maryann mentioned.

Regarding Stephanies post on quinine for leg cramps, I am researching possible alternatives. Quinine has been used for...

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