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Search: Posts Made By: gdpawel
Forum: Articles of Interest 11-19-2011, 08:47 AM
Replies: 6
Views: 2,969
Posted By gdpawel
Compassionate Use for Avastin?

Some industry-insiders have suggested the Compassionate Use Program could work for Roche, with Avastin. Now that the FDA has rejected Avastin for breast cancer, breast cancer now becomes a...
Forum: Articles of Interest 11-19-2011, 08:45 AM
Replies: 6
Views: 2,969
Posted By gdpawel
FDA Yanks Breast Cancer Indication For Avastin

Ed Silverman
Pharmalot.com

After more than a year of controversy and anticipation, the FDA has decided to formally yank the breast cancer indication for Avastin after deciding the widely used...
Forum: Articles of Interest 11-18-2011, 12:02 PM
Replies: 6
Views: 2,969
Posted By gdpawel
FDA Withdraws Avastin's Breast Cancer Indication

According to Merriall Goozner (who occasionaly writes for the Journal of the National Cancer Institute), two clinical trials showed no improvement in mortality among women with metastatic breast...
Forum: Articles of Interest 07-18-2011, 08:26 PM
Replies: 6
Views: 2,969
Posted By gdpawel
With Low-dose Chemotherapy - You Wouldn't Need Avastin

Many chemotherapy drugs, in addition to killing tumor cells, also fight angiogenesis. However, the anti-angiogenic effects of dose-dense therapy may be masked and marginalized by the way it is...
Forum: Articles of Interest 07-09-2011, 10:44 AM
Replies: 6
Views: 2,969
Posted By gdpawel
The Avastin Saga Continues

[Dr. Robert A. Nagourney is medical director at Rational Therapeutics and instructor in Pharmacology at the University of California, Irvine School of Medicine. He posted on his blog about the issue...
Forum: Articles of Interest 06-28-2011, 10:12 AM
Replies: 6
Views: 2,969
Posted By gdpawel
Re: Changing End Points in Breast-Cancer Drug Approval — The Avastin Story

In regards to changing endpoints, a summary of clinical trial data presented at the ASCO 2010 Kamofsky Memorial Lecture was presentated at a industry supported symposium at the SGO 2011 meeting on...
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