Forum: Breast Cancer News
12-24-2011, 11:14 AM
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Replies: 13
Views: 9,427
Re: Zometa in adjuvant for younger women
Looking at the various info above, seems to me the balance tips towards benefit. Downside probably eth usual additional kidney stress and the controversial osteonecrosis of jaw and fracture risk. All...
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Forum: Breast Cancer News
12-23-2011, 11:52 AM
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Replies: 13
Views: 9,427
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Forum: Breast Cancer News
12-21-2011, 10:12 PM
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Replies: 13
Views: 9,427
Re: Zometa in adjuvant for younger women
Well..helpful in ER+, helpful in ER-..and in her2 + mice:
J Cell Mol Med. (http://www.ncbi.nlm.nih.gov/pubmed/19818098#) 2010 Dec;14(12):2803-15. doi: 10.1111/j.1582-4934.2009.00926.x.
Zoledronic...
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Forum: Breast Cancer News
12-21-2011, 07:10 PM
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Replies: 13
Views: 9,427
Re: Zometa in adjuvant for younger women
On the other hand...might have an argument to take Zol preventatively based on.....
Mol Cancer Ther. (http://www.ncbi.nlm.nih.gov/pubmed/21393426#) 2011 May;10(5):732-41. Epub 2011 Mar 10.
CCN1,...
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Forum: Breast Cancer News
12-20-2011, 09:48 PM
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Replies: 13
Views: 9,427
Re: Zometa in adjuvant for younger women
After reading the free paper, I don't get the sense the current research addresses ER-/Her2+. situation one way or the other. Keep in mind they are talking about benefits of Zometa beyond the usual...
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Forum: Breast Cancer News
12-20-2011, 01:47 AM
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Replies: 13
Views: 9,427
Re: Zometa in adjuvant for younger women
This article is not exactly clear. Seems to be suggesting benefit is greater when circulating estrogen is minimal.
Here is an abstract from Gnant:
Breast Dis....
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Forum: Breast Cancer News
12-09-2011, 12:26 AM
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Replies: 13
Views: 9,427
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