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Search: Posts Made By: donocco
Forum: her2group 02-08-2019, 11:03 AM
Replies: 114
Views: 10,687
Posted By donocco
Re: Treatment after Kadcyla?

Jules

I hope other people put in their input but if you can get Herceptin with the Eribulin it would seem the way to go. Im sorry you are having problems with the medical board.

I tell ...
Forum: her2group 02-05-2019, 03:28 PM
Replies: 114
Views: 10,687
Posted By donocco
Re: Treatment after Kadcyla?

Jules

I took a quick glance at DS8201. It is Herceptin combined with Deruxtecan and seems to have a good effect in the phase i studies. I tried to find out what Deruxtecan is and didnt have much...
Forum: her2group 02-03-2019, 10:46 PM
Replies: 114
Views: 10,687
Posted By donocco
Re: Treatment after Kadcyla?

Jules

The Acetaminophen in Co-Codomal has been known to lower platelets but it isnt that common.
Could the low platelets be due to another drug? From the cases I read, when the acetaminphen is...
Forum: her2group 02-02-2019, 12:40 PM
Replies: 114
Views: 10,687
Posted By donocco
Re: Treatment after Kadcyla?

Jules

Epirubicin for all intents and purposes is a form of Adriamycin.It is an Anthracycline chemical and has the same side effects as Adriamycin such as hair loss, mouth sores, low white cell...
Forum: her2group 01-26-2019, 12:03 PM
Replies: 16
Views: 453
Posted By donocco
Re: Pericarditis Query

Lani

I had no idea of this. Colchicine comes from a plant, the meadow saffron. Colchis was the old name for the area of Russia known as Georgia (the south part bordering on the black sea where the...
Forum: her2group 01-21-2019, 12:40 PM
Replies: 16
Views: 453
Posted By donocco
Re: Pericarditis Query

Marie

Ill research pericarditis but I do have a question that popped into my mind.
As a child did you ever have a problem with rheumatic fever. I remember in my last year of
Pharmacy school I...
Forum: her2group 01-20-2019, 11:08 PM
Replies: 16
Views: 453
Posted By donocco
Re: Pericarditis Query

Technically the word Pericarditis (the itis part) implies some kind of infection. I know the anti Her2neu drugs can affect heart function but they wouldnt cause an infection unless the side effect...
Forum: her2group 01-19-2019, 06:40 PM
Replies: 114
Views: 10,687
Posted By donocco
Re: Treatment after Kadcyla?

Juls

Go to google. There were cases in Denmark in 1993 where breast cancer patients who took
390mg Coenzyme Q10 daily had the mets cleared. Interesting. You would think everybody would know od...
Forum: her2group 01-03-2019, 11:07 PM
Replies: 8
Views: 915
Posted By donocco
Re: Two Chemo drugs linked to BC spread

Cutie P

In the science world its publish or perish. We have been taken over by cancer. Just watch TV for an hour. First the box talks to you about colon cancer and measuring the DNA in your...
Forum: General Cancer News 12-04-2018, 02:11 PM
Replies: 1
Views: 727
Posted By donocco
Re: Researchers find two connective tissue cells to be linked to worse prognosis of b

They dont mention this specifically but on eof the main cancer growth metastasis etc stimulating chemicals is a Cytokine called Interleukin-6. This is what these fibroblasts in the tumor environment...
Forum: her2group 11-13-2018, 10:52 PM
Replies: 12
Views: 1,559
Posted By donocco
Re: 13 years!!!

Im late too. Many congrats


Paul
Forum: her2group 11-13-2018, 11:09 AM
Replies: 84
Views: 8,861
Posted By donocco
Re: ZW25 clinical trial - day one

I would question the doctor. Keytruda can have serious even fatal side effects but the side effects are immunological. The T cells become too active and can cause auto-immune disease. If this occurs...
Forum: Inflammatory Breast Cancer 11-07-2018, 02:06 PM
Replies: 3
Views: 1,281
Posted By donocco
Re: IBC ( inflammatory breast cancer)

There is an enzyme very involved with IBC called Anaplastic Lymphoma Kinase. About 90%
of inflammatory breast cancers are partially driven by the abnormal functioning of this enzyme. There is...
Forum: her2group 10-31-2018, 10:33 AM
Replies: 18
Views: 2,687
Posted By donocco
Re: Sleepness nights after chemo

You are correct that Ativan is technically not an anti-nausea drug. Some cases of nausea and vomiting are partly psychological. The patient remembers past nausea and vomiting and
anticipates the...
Forum: her2group 10-28-2018, 12:05 PM
Replies: 18
Views: 2,687
Posted By donocco
Re: Sleepness nights after chemo

The name of the anti-nausea drug that causes drowsiness probably was Ativan, generic name Lorazepam.
Forum: Breast Cancer Newsfeed 10-24-2018, 12:09 PM
Replies: 1
Views: 1,026
Posted By donocco
Re: Immunotherapy successful against deadly breast cancer

The new imunotherapy drug isnt really new. it is another PD1 inhibitor with a brand name of Tecentriq. My computer was down and I was a bit frustrated because I was curious about Tecentriq thinking...
Forum: General Cancer News 10-03-2018, 10:23 AM
Replies: 2
Views: 432
Posted By donocco
Re: Scientists perform successful trial of new antibiotic on cancer reoccurrence afte

It may be Zinc more than Calcium although both seem to be involved. I hate to split hairs but I want to be accurate. Both Zinc and Calcium (and the iron in Ferrous sulfate) are divalent (two positive...
Forum: General Cancer News 10-03-2018, 10:03 AM
Replies: 2
Views: 432
Posted By donocco
Re: Scientists perform successful trial of new antibiotic on cancer reoccurrence afte

Very Interesting.
Ive always believed that the key to fighting cancer will be by using old drugs. Actually Doxycycline is a Tetracycline derivative. It has been known for years if not decades that...
Forum: Breast Cancer Newsfeed 09-30-2018, 11:39 AM
Replies: 1
Views: 1,216
Posted By donocco
Re: Can aspirin help treat cancer?

The use of Aspirin as a cancer treatment makes sense. One Caveat. Dont self medicate without the doctors knowledge. Asprinin reduced fever. If you are on any drug that lowers
the neutrophil count...
Forum: her2group 09-13-2018, 10:20 PM
Replies: 17
Views: 4,882
Posted By donocco
Re: Medical Marajuna Girls

I called Walgreens in Huntington Beach California and asked the price of thirty 25mg Movantik tablets without insurance. It is usually taken once daily. It was cheaper than I thought-four Hundred one...
Forum: her2group 09-13-2018, 10:05 PM
Replies: 17
Views: 4,882
Posted By donocco
Re: Medical Marajuna Girls

Cathy

Fast tracking the drug may well be a reason. Im not sure it is the only one. I reasoned pharmacologically that Ibrance could be used in Her2 Neu positive patients. I was t sure. sometimes...
Forum: her2group 09-13-2018, 05:34 PM
Replies: 17
Views: 4,882
Posted By donocco
Re: Medical Marajuna Girls

Ibrance is a fairly good drug. Some advances have been made. But the underlying suffering from cancer has not changed much in the fourty years I mentioned.

Its a crap shoot really. Some people...
Forum: her2group 09-13-2018, 10:12 AM
Replies: 17
Views: 4,882
Posted By donocco
Re: Medical Marajuna Girls

I agree with you 1000%. I worked as a pharmacist at Sloan Kettering in 1978. That was 40
years ago. It was a difficult place to work. You could cut the fear and guilt etc etc with a knife....
Forum: her2group 09-09-2018, 10:18 AM
Replies: 10
Views: 2,708
Posted By donocco
Re: Chemo Not Needed for Most Early Breast Cancer: TAILORx

Chemo kills a percentage of cells. Say 99.9%. There are still many cancer cells left and the survivors are resistant to the chemo that killed 99.9% of their "siblings." In time these survivors grow...
Forum: her2group 09-05-2018, 09:33 PM
Replies: 7
Views: 2,057
Posted By donocco
Re: DS-8201A Trial

I looked up the drug. It is Herceptin conjugated with a Topoisomerase 1 inhibitor. This class of chemo drugs can cause ocular problems. Just a pharmacological guess but it makesd sense. Ask the doc...
Showing results 1 to 25 of 326

 
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